Discutii despre coronavirus

[Utilizator]

Deh, nemtii sunt mai prosti, nu asculta de sosocii lor si se lasa omorati de BigPharma. Ma rog, au si avantaje din asta, la ei 5G zbarnaie si nu mai au nevoie de antene de retransmisie. Si au capacitate mai mare de memorie si de prelucrare a datelor de la cipurile lui Gates.

[Julio_Zane]

Update :

Am avut Covid in februarie, am scapat cu viata la mijlocul lui martie. Cu tot riscul asumat, m-am vaccinat la sfarsitul lui iulie.
Acum sunt ok, dar inca se mai simt efectele de dupa.

[miril]

Excelent articol despre noua mutatie, omicron.

Omicron variant reaches Britain: yes, it’s worrying, but scientists are preparing our defences

The new strain’s mutations suggest it could be fast-spreading and able to evade vaccines — but let’s not panic just yet

On Monday morning, four long days before anyone had heard of the Omicron variant, an announcement was made by the health department in Pretoria, one of South Africa’s capital cities.

A cluster of new Covid cases had emerged at Tshwane University of Technology, which health officials assumed had been caused by an increase in socialising in the run-up to Christmas. The nearby townships of Atteridgeville, Mamelodi and Soshanguve were also seeing rising numbers of infections. Cases in the city and surrounding area had risen four-fold in a week. “While it might be too early to talk about the fourth wave being in our midst, now is not the time to let our guard down,” the department’s announcement said. By the end of the week it was clear this surge not only threatened to envelop South Africa, but also marked the most worrying development in the pandemic since the Delta variant emerged from India last spring.

A constellation of mutations
While officials in Pretoria were worrying about resurgent cases in student dorms, in nearby Botswana scientists were growing concerned about an unusual set of Covid samples taken from three patients. The test samples, the first of which dated back to November 11, revealed a new variant, displaying an unprecedented 50 mutations. Scientists were startled: this was not just a gradual shift, it was an evolutionary leap. Worryingly, a fourth sample with the same genetic sequence was recorded in Hong Kong from a patient who had travelled from South Africa.

The new variant — at that point unnamed — was particularly concerning because the spike protein, the protrusion on the outside of the virus, had 30 different mutations. By comparison, the Delta variant, which ripped across the world in the spring, only had 13 spike mutations.

Such a dramatic evolution has two significant ramifications. Firstly, the key vaccines in use around the world — Pfizer, Moderna and AstraZeneca — work by teaching the immune system to recognise the spike protein. If the spike protein has significantly changed, antibodies might no longer recognise it quite so well. Our hard-won immunity might be side-stepped.

Secondly, ten of the mutations seen in the new variant were on the receptor-binding domain, the specific part of the spike protein that attaches to human cells. Delta has only two such mutations. The better the ability to attach to cells, the theory goes, the more transmissible the virus is. And the more transmissible it is, the faster it will spread.

Joining the dots
Tom Peacock, a virologist at Imperial College London, was one of the first outside southern Africa to spot the implications of the new variant. But while he was concerned about the number of mutations and the “horrific spike profile”, he initially took a measured approach. Writing on Twitter on Tuesday, he said: “Worth emphasising this is at super-low numbers right now in a region of Africa that is fairly well sampled.” But scientists in South Africa were joining the dots, and realised the surge in Pretoria was caused by the same mysterious mutation spotted in Botswana. Within a couple of days it had become apparent that Peacock’s “super-low” numbers were in fact a lot, lot higher.

The speed with which this link was made is remarkable. Last year it took two months for scientists to realise that a mysterious spike in cases in Kent was caused not by socialising, as first thought, but by the new Alpha variant. It took even longer for the Delta variant, which emerged at around the same time in India, to be recognised, and even longer than that for the world to do anything about it.

This time, there were no delays. On Thursday Professor Tulio de Oliveira of the University of KwaZulu-Natal — the same scientist who 12 months earlier alerted the world to the presence of a previous worrying variant, now known as Beta — held an impromptu press conference. He revealed rapid analysis of testing samples suggested 90 per cent of cases in Gauteng province — which includes the cities of Pretoria and Johannesburg — might have been caused by the new variant. Oliveira said scientists’ theoretical fears about transmissibility looked correct, with cases surging. He predicted 1,000 people were being infected with the new strain in Gauteng daily. And there were signs it had already spread across the country.

The reaction was immediate. Within hours the UK had put South Africa and five bordering countries onto its travel red list and suspended direct flights. A senior UK government scientist that night described it as “the worst variant we have seen so far”.

On Friday the World Health Organisation labelled it a “variant of concern” and gave it the name Omicron, after the 15th letter of the Greek alphabet. Cases were reported in Belgium and Israel. Some £85 billion was knocked off the value of the London stock indexes as the market panicked, the worst performance in a day since the end of March 2020.

By the weekend the inevitable had happened. Omicron had reached our shores.

So now that it is here, how serious is it?
In truth, it is too early to tell. Worries about transmissibility seem justified — the rapid spike in cases in Gauteng, and its rapid travel around the world, suggest it can spread incredibly quickly.

Perhaps a bigger worry is whether it will evade our vaccines. That is harder to tell. The genomics do not look good — the mutations to the spike protein are clearly worrying. But this is a theoretical risk and we will not know the impact until scientists have properly assessed the variant against antibodies and vaccines. The first antibody lab results will be due in a few days and Pfizer says it will be able to give an assessment as to how its vaccine performs within a fortnight.

Even then, we will only know the scale of the Omicron threat for sure when it comes up against vaccines in the real world. The rapid spread in South Africa might be partly explained by the fact that only 24 per cent of the po****tion has received two doses of a Covid vaccine. In the UK that figure is 69 per cent.

There are reasons to be hopeful. Professor Sir Andrew Pollard, director of the Oxford Vaccine Group, believes the existing jabs will cope against the new variant, pointing out that although there are a lot of mutations, most are in similar regions seen in other variants so far — each of which have been effectively dealt with by the original vaccines without reformulation.

Even if the new variant manages to sidestep the antibodies produced by the vaccine, it is unlikely to escape our immunity altogether. T-cells, a different type of immune response triggered by the vaccine, are far less specific than antibodies, so even if immunity is reduced, it is unlikely to be eradicated completely. Booster jabs will help to drive up this protection. As Pollard, speaking to BBC Radio 4’s Today programme, put it yesterday, “It’s extremely unlikely that a reboot of a pandemic in a vaccinated pop.ulation like we saw last year is going to happen.”

Another crucial question is whether Omicron will be able to make inroads into the UK at all. To do so it would need to displace the Delta variant. Previous worrying strains — including the Beta variant and the Gamma variant, which emerged from Brazil — faded away because they could not compete, first against the Alpha variant, and then against the Delta strain.

While soaring cases in South Africa, where Delta was previously dominant, do not inspire confidence that Delta can hold firm against Omicron, until a fortnight ago there were no more than 100 cases a day in the entire country. In the UK, where cases are hitting more than 50,000 a day, Delta might be harder to shift.

An outlier? Or the first of many?

Not necessarily. We will never know where it originated — Botswana, South Africa, or somewhere else. But scientists believe whatever its origin, such a dramatic evolution is likely to have taken place in an immunocompromised patient — for example someone with HIV who was unable to fight off a Covid infection, which then mutated within their body. Professor Ravi Gupta of Cambridge University, who has documented such a mutation taking place in
one of his patients, believes the new variant has similar “signatures of cumulative mutation, indicating that it emerged in a chronic infection”.

Why does this matter? Because it suggests we are not where we were this time last year, when four dangerous variants — Alpha, Beta, Gamma and Delta — emerged around the world in the space of a few weeks. That process happened because of evolutionary pressure to adapt to the human body, 12 months after the virus emerged from bats. Since then, Delta, the evolutionary winner, has been remarkably stable. It has changed in subtle ways, but

not to a worrying extent. If the Omicron variant is, as suspected, the result of a mutation within a single very sick patient, it suggests this is a piece of bad luck rather than an evolutionary inevitability — in other words, an outlier. And that means another wave of ever more devastating mutants is not necessarily on the horizon.

Are we ready?
We are in for a nervous few weeks, yet again, while we see how far and fast the variant spreads through the British pop.ulation and what impact it has along the way.

But our defences are now primed. We have the best genomic surveillance in the world, and while NHS Test and Trace has been scaled down its staff are still active with 50,000 cases a day.

And once more, we can put our trust in science to come to the rescue. If it turns out the new variant escapes our immunity, scientists are ready tweaking vaccines to tackle the new threat. On Friday night — just three days after scientists in Botswana published the genetic sequence for the new virus — Moderna announced it was already preparing an Omicron-specific booster vaccine. Pfizer is ready to do the same.

Pollard says the Oxford team is ready to act, if needed. “The processes of how one goes about developing a new vaccine are increasingly well oiled,” he said. In six weeks new vaccines could be ready and, if needed, in 14 weeks would be ready for mass roll-out.

The health officials of Pretoria got it right, at the beginning of the week, when they said it was not the time to let our guard down. But, equally, it is not the time to panic. Omicron is here. But the scientists are ready.

https://www.thetimes.co.uk/article/o...tain-p7ddffjkt

Scuze ca articolul nu este "asezat" bine. Prea multe reclame!

[delaparis]

De luni vin masuri sanitare iar in Franta.
5000 de spectatori maxim pe stadioane, 2000 in sali, la restaurant trebuie pasaport sanitar dar si test de mai putin de 24 ore, teleworking etc ...
Ne paste isolarea peste cateva saptamani

[Novac]

pai aveti plus o suta de mii de cazuri noi/ zi

ce te astepti?

[Novac]

De luni vin masuri sanitare iar in Franta.
:

pardon, de vineri
https://www.hotnews.ro/stiri-coronav...and-vineri.htm


Ps. Ah, si cica aveti +200.000

[delaparis]

Ca de obicei informatia, desi exacta, este incompleta. Astfel devine propaganda.
Reperul central este numarul de admisii la urgenta in spital. Acesta e constant de trei luni.
Da, se explica prin faptul ca in perioada de sarbatori francezii fac coada la testari si de aia cazurile constatate urca abrupt. Dar de fapt nu sunt mai multi infectati ci sunt mai multi detectati.
Virusul circula indiferent daca esti vaccinat sau nu. Esti pozitiv chiar si cu 3 doze de vaccin daca esti in contact. Vaccinul te protejeaza doar ca sa nu dezvolti forme grave si complicatii etc ...

Problema Frantei nu e ca le e teama de morti sau raniti . Problema e ca legea prevede izolare daca esti pozitiv la test deci pericol ca milioane de absenti de la munca. Tara e paralizata birocratic desi majoritatea e vaccinata. Absurditatea masurilor sanitare ...

[delaparis]

Azi am primit a treia doza vaccin, Moderna, desi primele doua au fost Pfizer. Am ceva efecte secundare. Ma doare in cot si ma simt mai inteligent

[miril]

Azi am primit a treia doza vaccin, Moderna, desi primele doua au fost Pfizer. Am ceva efecte secundare. Ma doare in cot si ma simt mai inteligent

...sase luni.

[delaparis]

Cel mult.
Gurile rele spun ca peste 4 luni mai trebuie o doza ... sa mentin nivelul

[miril]

Trebuie sa stam bine cu mentenanta!

[Utilizator]

mai vedem, mai discutam, este destul de evident ca nu putem merge la nesfarsit cu 3 vaccinari anuale numai pentru covid.
din ce am mai citit pare ca virusul urmeaza cursul normal si se domoleste prin mutatii, respectiv vom iesi din pandemie anul asta.
cu siguranta ca si vaccinurile vor evolua si drept urmare cred ca vom ajunge la o vaccinare anuala precum cea de gripa sezoniera.

[cip]

Booster si eu luna asta,toate cu Moderna...sper ca nu mi-au implantat astia vreun cip...
Efect secundar, am prins si mai multa ciuda pe Dinamo...

[Capitanu.Burcea]

https://www.libertatea.ro/stiri/o-ca...edium=referral

Nu ai cum sa nu iubesti acest virus.

[Utilizator]

Mda, unii vor sa creada mai mult decat incearca sa inteleaga si nu se lasa pana cand nu se ard singuri.

Ma intreb daca omenirea evolueaza sau involueaza, daca pe vremea ciumei sau a holerei erau capsomani precum astia de azi care considerau molimele drept o manevra a statului ca sa-i tina in case.
Ma rog, pe atunci carantina pentru aia pozitivi insemna sa le bata usa-n cuie. Nu aveau botnita, vaccinuri si alte mijloace moderne de protectie.
Astazi probabil ca cel mai eficient mod de a reveni la normal ar fi un virus letal pentru platformele de social-media unde prostii satului si escrocii au devenit vedete.

[JJ]

Acum 150-200 de ani antivaxxerii strigau ca ai mari sanse sa te transformi in bou, daca risti sa-ti faci vaccinul contra variolei.

[delaparis]

Iar azi, ei se transforma ...

[Utilizator]

Acum 150-200 de ani antivaxxerii strigau ca ai mari sanse sa te transformi in bou, daca risti sa-ti faci vaccinul contra variolei.

corect, denumirea de vaccin chiar vine de la vaca, primul vaccin cunoscut, cel contra varicelei al lui E. Jenner, era pe baza de varicela bovina.
si iete ca tocmai aia nevaccinati au murit ca boii iar varicela fusese eradicata pana de curand cand au aparut alti boi care se opun vaccinarii si vor sa ii aduca gloria de altadata.

Dar inainte de asta nu prea erau vaccinuri ca sa domoleasca pandemiile, erau doar "dictaturi sanitare" de limitare a daunelor.

[JJ]

Uti, e vorba de variola nu varicela. Varicela inca e bine merci, nici nu cred ca se vaccineaza de exemplu in Romania.

[Utilizator]

Greseala mea, ai dreptate!

[delaparis]

Covid nu mai este la moda?